Return to MEDLINE Data Changes—2021 article

New MeSH Headings Related to COVID-19 and SARS-CoV-2

MeSH Heading	Status and Other Notes
Coronavirus 3C Proteases	was an SCR; promoted to a new MeSH heading.
Coronavirus Envelope Proteins	new MeSH heading
Coronavirus M Proteins	was an SCR; promoted to a new MeSH heading.
Coronavirus Nucleocapsid Proteins	was an SCR; promoted to a new MeSH heading.
Coronavirus Papain-Like Proteases	was an SCR; promoted to a new MeSH heading.
Coronavirus Protease Inhibitors	new MeSH heading
Coronavirus RNA-Dependent RNA Polymerase	was an SCR; promoted to a new MeSH heading.
COVID-19	was an SCR; promoted to a new MeSH heading.
COVID-19 Nucleic Acid Testing	was an entry term to COVID-19 diagnostic testing.
COVID-19 Serological Testing	was an entry term to COVID-19 diagnostic testing.
COVID-19 Testing	was an SCR (COVID-19 diagnostic testing); promoted to a new MeSH heading.
COVID-19 Vaccines	was an SCR; promoted to a new MeSH heading.
Receptors, Coronavirus	was an SCR; promoted to a new MeSH heading.
SARS-CoV-2	was an SCR; promoted to a new MeSH heading.
Spike Glycoprotein, Coronavirus	was an SCR; promoted to a new MeSH heading.

Other New MeSH Headings of Interest to Searchers for COVID-19 and SARS-CoV-2

MeSH Heading	Status and Other Notes
3C Viral Proteases	new MeSH heading
Angiotensin-Converting Enzyme 2	was an SCR; promoted to a new MeSH heading. Angiotensin Receptors is an existing MeSH heading.
Anosmia	new MeSH heading
Chain of Infection	new MeSH heading
Disease Hotspot	new MeSH Heading Disease Reservoir is an existing MeSH heading.
Host Adaptation	new MeSH heading
Latent Infection	new MeSH Heading Do not confuse with Reinfection or Recurrence.
N95 Respirators	new MeSH heading
Pangolins	new MeSH heading
Physical Distancing	new MeSH Heading Social Distancing is an entry term. Do not confuse with Psychological Distance.
Positive-Strand RNA Viruses	new MeSH Heading SARS-CoV-2 is a Positive-Strand RNA Virus.
Prolyl Oligopeptidases	new MeSH heading
Reinfection	new MeSH Heading Do not confuse with Latent Infection or Recurrence.
Return to School	new MeSH heading Return to Work and Return to Sport are existing MeSH headings.
Teleworking	new MeSH heading
Viral Envelope	new MeSH heading
Viral Genome Packaging	new MeSH heading
Viral Packaging Sequence	new MeSH heading
Viral Papain-like Proteases	new MeSH heading
Viral Replicase Complex Proteins	new MeSH heading
Viral Replication Compartments	new MeSH heading
Viral Transcription	new MeSH heading
Viral Zoonosis	new MeSH heading

Please refer to the complete list of new 2021 MeSH headings (PDF format) for other terms that might be relevant to COVID-19 and SARS-Cov-2.

Supplementary Concept Records (SCRs) Related to COVID-19 and SARS-CoV-2

SCR	Heading Mapped To
2019-novel coronavirus real-time reverse transcriptase diagnostic panel	COVID-19 Nucleic Acid Testing
3C-like proteinase, SARS-CoV-2	Coronavirus 3C Proteases
Ad5-nCoV vaccine	COVID-19 Vaccines
BNT162 vaccine	COVID-19 Vaccines
ChAdOx1 COVID-19 vaccine	COVID-19 Vaccines
Covid-19 aAPC vaccine	COVID-19 Vaccines
COVID-19 drug treatment	Coronavirus Infections / drug therapy
COVID-19 post-intensive care syndrome	COVID-19 / complications
COVID-19 serotherapy	Immunization, Passive Coronavirus Infections / therapy
COVID-19 stress syndrome	COVID-19 / complications
envelope protein, SARS-CoV-2	Coronavirus Envelope Proteins
GS-441524 (is a metabolite of remdesivir)	Furans Pyrroles Triazines
INO-4800 vaccine	COVID-19 Vaccines
LAMP assay	Nucleic Acid Amplification Techniques Molecular Diagnostic Techniques
lentiviral minigene vaccine of COVID-19 coronavirus	COVID-19 Vaccines
membrane protein, SARS-CoV-2	Viral Matrix Proteins
M protein, Human coronavirus OC43	Coronavirus M Proteins
mRNA-1273 vaccine	COVID-19 Vaccines
NSP1 protein, SARS-CoV-2	Viral Nonstructural Proteins
nsp2 protein, SARS-CoV-2	Viral Nonstructural Proteins
NSP3 protein, SARS-CoV-2	is an entry term to papain-like protease, SARS-CoV-2
NSP4 protein, SARS-CoV-2	Viral Nonstructural Proteins
NSP5A protein, SARS-CoV-2	is an entry term to 3C-like proteinase, SARS-CoV-2
NSP6 protein, SARS-CoV-2	Coronavirus Nucleocapsid Proteins
NSP7 protein, SARS-CoV-2	Coronavirus RNA-Dependent RNA Polymerase
NSP8 protein, SARS-CoV-2	Coronavirus RNA-Dependent RNA Polymerase
NSP9 protein, SARS-CoV-2	RNA-Binding Proteins Viral Nonstructural Proteins
NSP10 protein, SARS-CoV-2	Viral Regulatory and Accessory Proteins
NSP12 protein, SARS-CoV-2	Coronavirus RNA-Dependent RNA Polymerase
nucleocapsid phosphoprotein, SARS-CoV-2	Coronavirus Nucleocapsid Proteins Phosphoproteins
ORF1ab polyprotein, SARS-CoV-2	Polyproteins Viral Proteins
ORF3a protein, SARS-CoV-2	Viroporin Proteins
ORF6 protein, SARS-CoV-2	Viral Proteins
ORF7a protein, SARS-CoV-2	Viral Proteins
ORF7b protein, SARS-CoV-2	Viral Proteins
ORF8 protein, SARS-CoV-2	Viral Proteins
papain-like protease, SARS-CoV-2	Coronavirus Papain-Like Proteases
pediatric multisystem inflammatory disease, COVID-19 related	COVID-19 Systemic Inflammatory Response Syndrome
PittCoVacc	COVID-19 Vaccines
post-acute COVID-19 syndrome	COVID-19 / complications
PREPL protein, human	Prolyl Oligopeptidases
remdesivir	Adenosine Monophosphate / *analogs & derivatives Alanine / *analogs & derivatives
remdesivir triphosphate	Adenosine Triphosphate / *analogs & derivatives
SARS-CoV-2 inactivated vaccines	COVID-19 Vaccines Vaccines, Inactivated
spike protein, SARS-CoV-2	Spike Glycoprotein, Coronavirus

Additional SCRs will be created as needed throughout 2021. Please continue to check the MeSH Browser for new SCRs.